The Paducah Woman's Club was organized in 1906, and formerly incorporated in 1907. The first clubhouse was located at 608 Kentucky Avenue, in 1908. It had formerly been the home of Mrs Anna Grief, widow of Martin Grief, who had been a dealer in picture frames and wallpaper in Paducah. In 1925, the clubhouse was remodeled, and a nice garden was added at the rear of the building. In 1937, the club met frequently at the Hotel Irvin Cobb. Later, the Woman's Club moved to its present location on Jefferson.